Varicella-Zoster Encephalitis Presenting with Trigeminal Neuralgia, Complicated by Vasculopathy

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Authors

Amy Ishbia, Corewell Health Resident
Kathy Ross, Corewell Health Resident
Dillon Yaldo, Corewell Health Resident
Jacob Conroy, Corewell Health Resident
Andrea Stoner, Corewell Health

Description

VZV is a herpesvirus that causes chickenpox before laying dormant and having the potential to reactivate to cause myelitis, encephalitis, or vasculopathy.

Encephalitis occurs in less than 0.1% of cases; however accounts for 90% of neurologic complications from VZV.

Vasculopathy is a rare complication of VZV encephalitis characterized by vessel wall damage and transmural inflammation with multinucleated giant cells and/or epithelioid macrophages.

Vasculopathy has significant morbidity/mortality due to ischemic/hemorrhagic stroke, spinal cord infarction, temporal artery inflammation, ischemic cranial neuropathies and cerebral venous thrombosis.

Publication Date

5-9-2024

Disciplines

Neurology | Radiology

Recommended Citation

Ishbia A, Ross K, Yaldo D, Conroy J, Stoner A. Varicella-Zoster encephalitis presenting with trigeminal neuralgia, complicated by vasculopathy. Presented at Corewell Health Hospital Farmington Hills 2024 Alvin Yarrows Research Day; 2024 May 9; Farmington Hills, MI.

Comments

2024 Alvin Yarrows Research Day at Corewell Health Hospital Farmington Hills, Farmington Hills, MI, May 9, 2024.