The Silent Crisis: Cardiovascular Mortality Among the Young Adults With Diabetes Mellitus

Document Type

Conference Proceeding

Publication Date

4-2-2024

Publication Title

Journal of the American College of Cardiology

Abstract

Background: Type 2 diabetes mellitus (DM) incidence in young adults has surged by >50% in past decades, yet there is limited real-world data on their cardiovascular mortality rates. Methods: We queried the CDC WONDER database among young adults (aged 15- 44) from 1999 to 2020. Cardiovascular disease was listed as the main cause of death, while DM was the contributing cause. We calculated age-adjusted mortality rates (AAMR) per 100,000individuals and determined annual percent changes (APC) by using the Join point regression program. Results: Among the 2,787,171,479 young adults, 32,880 had DM and died from cardiovascular causes. The overall AAMR increased significantly from 1.08 (95% CI, 1.02-1.14) in 1999 to 1.63 (95% CI, 1.56- 1.71) in 2020, with an average APC of 0.96 (95% CI, 0.48- 1.43).Excluding unspecified cases, 2,947 (42.9%) had Type I DM and 3,926 (57.1%) had Type II. The AAMR among patients with DM increased by 44.2%, compared to a decrease of 4.8% in those without. Males had a higher AAMR than females (1.60 [95% CI, 1.57 - 1.62] vs. (1.01[95% CI, 0.99 -1.02]). Among all races, African Americans had the highest AAMR (3.03 [95% CI, 2.97 - 3.09]). South region had the highest AAMR (1.55 [95% CI, 1.53 - 1.58]) whereas AAMR was higher in the rural than urban area (1.66 [95% CI, 1.62 - 1.71] vs. 1.23 [95% CI,1.21- 1.24]).Conclusion: The rise of cardiovascular deaths in young adults with diabetes reveals notable demographic and geographical differences, underscoring the need for tailored healthcare policies.

Volume

83

Issue

13 Suppl

First Page

1714

Comments

American College of Cardiology 73rd Annual Scientific Session & Expo, April 6-8, 2024, Atlanta, GA

DOI

10.1016/S0735-1097(24)03704-5

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