The Asian Heartbeat in America: Dissecting Valvular Heartdisease Trends Over Two Decades

Document Type

Conference Proceeding

Publication Date

4-2-2024

Publication Title

Journal of the American College of Cardiology

Abstract

Background: Transcatheter valve interventions have grown in recent decades, yet real-world mortality data of valvular heart diseases (VHD) among the Asian American population remains limited. Methods: We queried the CDC WONDER database among patients ≥ 15 years old from 1999 to 2020. VHD was listed as the underlying cause of death. Asian American subgroup data was available from 2018 to 2020. We calculated age-adjusted mortality rates (AAMR) per 1,000,000 individuals and determined annual percent changes (APC) by using Joinpoint regression program. Results: Among the 298,659,717 Asian Americans ≥ 15 years old, 7,723 died from VHD (1.9% of the total cardiovascular deaths). The AAMR of VHD decreased from 5.0 (95% CI, 4.3-5.7) to 3.1 (95% CI, 2.8-3.4) with an average APC of -1.3 (95% CI, -1.7- -0.8). The most prevalent VHD was aortic valve (59.5%), followed by mitral valve (31.1%), tricuspid valve (2.9%), and pulmonary valve diseases (0.1%). Males recorded higher average APC compared to females (-1.4 [95% CI, -2.3 - -0.5] vs -1.2 [95% CI, -1.8 - -0.6]). The top three Asian American subgroups with the highest proportionate mortality were Filipino (25.1%), Japanese (20.2%), and Chinese (19.6%). Geographically, West region had the highest AAMR of VHD (4.5 [95% CI, 4.4-4.6]). The AAMR was higher in rural areas than in urban areas (5.9 [95% CI, 5.3-6.4] vs. 3.7 [95% CI, 3.6-3.8]). Conclusion: The mortality rate from VHD among Asian Americans has declined, but future effort is needed to address the demographic disparities.

Volume

83

Issue

13 Suppl

First Page

2176

Comments

American College of Cardiology 73rd Annual Scientific Session & Expo, April 6-8, 2024, Atlanta, GA

DOI

10.1016/S0735-1097(24)04166-4

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