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Iatrogenic nerve injuries during surgeries of the neck: a systematic review
Tajuldeen Al-Hasani, Jickssa Gemechu, and Varna Taranikanti
Publication Date: 5-2023
Iatrogenic nerve injuries in the neck can present with a wide spectrum of symptoms ranging from mild pain, numbness, or weakness, to devastating consequences for patients such as permanent irreversible damage, disability, or even death. Surgical interventions in the neck region, especially those requiring radical dissections in the neck carry a significant risk of iatrogenic injury to several vital nerves passing through the neck such as vagus, phrenic, brachial plexus, cervical plexus, and ansa cervicalis.
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Beyond COVID-19: The Impact of Recent Pandemics on Medical Students and their Education: A Scoping Review
Moneb Bughrara, Stephanie Swanberg, Victoria Lucia, Keaton Schmitz, Dawn Jung, and Tracy Wunderlich-Barillas
Publication Date: 5-2023
Over the past two years, COVID-19 has greatly altered undergraduate medical education (UME) as well as daily life. Medical schools across the world were disrupted and had to immediately adapt the educational experience to the online environment in order to continue the delivery of quality UME. However, COVID-19 was not the only recent pandemic. This posed the question, were similar disruptions and adaptations also seen in recent past pandemics such as Severe Acute Respiratory Syndrome (SARS) or Middle East Respiratory Syndrome (MERS) that could have prepared UME for COVID-19? This scoping review investigated the educational and personal impact of recent pandemics on UME and medical students.
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Telemedicine Success - A Rapid Review
Anna Carman and Victoria Lucia
Publication Date: 5-2023
Telemedicine involves utilizing telecommunications and technology to deliver healthcare - including diagnosis, consultation, education, care management, and patient self-management - to populations with otherwise limited access to care. It offers a broad-range of benefits, including increased care accessibility, improved continuity of care, and decreased costs, without sacrificing patient satisfaction. However, telemedicine requires unique skills and approaches, unfamiliar to many physicians. We conducted a rapid review of research-validated techniques, across multiple subspecialties, to identify research-validated techniques for maximizing telemedicine appointments, synthesized in a comprehensive list, in order to support clinicians in modern healthcare settings.
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Analysis of the Efficacy of the Modified Finnegan Scoring System
Benjamin Collaer and Victoria Lucia
Publication Date: 5-2023
Neonatal Abstinence Syndrome (NAS) is a constellation of opiate withdrawal symptoms including irritability, inadequate feeding/ growth, and seizures in neonates This condition occurs shortly after birth if the fetus had significant exposure to opiates in-utero. Since 2014, each NAS case at Beaumont Royal Oak and Troy Hospitals has had their treatment dictated by their score on the Modified Finnegan Scoring System (MFSS). This scoring system was created to minimize unnecessary opiate-based treatments for neonates with NAS. The main objective of this study is to analyze the efficacy of the MFSS and observe the change in patient outcomes since its implementation in 2014.
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Chief Complaint and Geriatric Depression: Assessing Risk for 30- and 90-Day Readmission
Eric James, Michelle Moccia, and Victoria Lucia
Publication Date: 5-2023
Readmission to the hospital has significant monetary costs and represents a care gap for older adults. This investigation examines how a positive geriatric depression screen and chief complaint contribute to 30- and 90-day readmission risk. Depression recognition with follow-up care is a critical first step to prevent adverse outcomes such as readmission.
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Incidence of Myopathy in Post COVID-19 Patients undergoing Statin Therapy
Jithin John, Eduardo Leon, and Ramin Homayouni
Publication Date: 5-2023
Statin-associated myositis has been documented since its first use, causing an increase in Creatinine Kinase levels. While some suggest avoiding statins in individuals with COVID-19, recent literature suggests that statin use is protective against SARS-CoV-2 infection due to its antioxidant and anti-inflammatory properties. The role of statin therapy in COVID-19 cases, especially regarding myopathy, remains scarce. We hypothesize that different statin therapies prior to SARS-CoV-2 infection are associated with an increased risk of myopathy and an increase in blood CK levels.
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A retrospective study on the incidence of CKD Diagnosis Post COVID-19 infection with variations in glycemic control
Eduardo Leon, Jithin John, Nick Ludka, and Ramin Homayouni
Publication Date: 5-2023
The COVID-19 pandemic has emphasized that the virus can cause multi-organ complications, especially in patients with pre-existing conditions such as type-2 diabetes mellitus (T2DM), who are at higher risk for poor outcomes. Some patients may also develop T2DM post-infection due to the virus's effects on insulin secretion and blood glucose regulation. Glycated hemoglobin (HbA1c) is a useful tool for assessing blood glucose levels over time, diagnosing diabetes and monitoring disease management. Elevated levels of HbA1c have been linked to diabetic nephropathy (DN) and chronic kidney disease (CKD), both of which are potential complications of COVID-19 infection. This study aims to investigate the development of CKD in patients with varying HbA1c levels, and other comorbidities after SARS-CoV-2 infection, hypothesizing that COVID-19 may accelerate the development of CKD in at-risk patients with higher levels of HbA1c.
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Effectiveness of a Modified Difficult Colonoscopy Score A Retrospective Review of General Surgeon Performed Colonoscopies at a Community Hospital
Killian Llewellyn, Lianne Caceres, Karen Childers, and John Parmely
Publication Date: 5-4-2023
Colonoscopy remains the mainstay of screening for colon cancer in the US and an essential operating room skill for general surgeons.
▪ A quality review was performed of general surgeons at a community hospital.
▪ Difficult Colonoscopy Score (DCS) was a score created to predict difficulty of colonoscopy which was defined as prolonged intubation time, need for external compression, or increased pain score [1]. We tested the utility in our community and resident-involved endoscopy department.
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Phenotype characterization of genetic murine mouse models of developmental dysplasia of the hip (DDH)
Stephanie Mrowczynski, Kevin Baker, and Michael Newton
Publication Date: 5-2023
Developmental dysplasia of the hip (DDH) is a congenital hip alteration that changes the “ball in socket” movement of the leg inside the pelvis. Genome-wide association studies have identified CX3CR1 polymorphisms associated with increased risk of Developmental Dysplasia of the Hip. Mouse models of CX3CR1 knock-out (KO) mice show unilateral, bony discrepancies between the femur head and acetabulum in comparison to wild-type (WT) mice, as well as gait impairment similar to that of humans with osteoarthritis (which develops in DDH patients later in life). The primary goal of this project is to assess joint congruity in a CX3CR1 KO model of unilateral developmental dysplasia of the hip and control populations via microcomputed tomography. The secondary goal is to evaluate bone and joint characteristics in CX3CR1 KO model of unilateral developmental dysplasia of the hip and control populations via microcomputed
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Traumatic Thoracostomy Tube Management at a Community Hospital A Retrospective Review
Christian Przeslawski, Peter Habib, Kita Mack, Vimal Love, Julie George, and Amelia Pasley
Publication Date: 5-4-2023
Thoracostomy tubes or chest tubes (CT) have been a mainstay in thoracic trauma treatment since the Vietnam war with their roots dating back to the 5th century [1]. Trauma is the number one cause of death in the world, with chest trauma being the second highest cause of trauma related death [2]. 18% of patients with a blunt thoracic injury require chest tube. Management varies widely and there is no general consensus on management [3].
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A comparative study of medication profiles from AD, MCI and non-demented patients
Md Golam Sharoar, Bhavya Koganti, Vaibhavkumar Falki, Zakia Zaman, Tammy Osentoski, and Stewart F. Graham
Publication Date: 12-2023
Background: The ever-increasing incidence of Alzheimer’s disease (AD) and the lack of effective therapeutics to treat the disease are leading to a “silver tsunami”. Current FDA-approved drugs to treat the disease are limited as their benefit is simply momentary relief of the symptoms. Due to the chronic and progressive nature of AD, patients are routinely prescribed multiple non-AD medications to preserve their ability to perform daily activities and to improve their quality of life. However, how those medications affect AD pathology remains unknown. In the present study, we have compared medication profiles of AD (n = 135), mild cognitive declined (MCI; n = 120), and non-demented (n = 259) patients, with an aim to determine the effects of top-ranked drugs on AD pathology.
Methods: Study subjects (≥65 years) were recruited from an academic geriatric practice that is heavily focused on memory disorders. All subjects underwent for the following cognitive assessments: a) Clinical dementia rating scale (CDR), b) MiniMental Status Examination (MMSE), c) logical memory test, d) digit span forward and backward, e) category fluency test, f) ordering test, g) trails A&B, and finally the Geriatric Depression Scale. Individual medication for each subject was listed and they were categorized into major drug classes. Statistical analysis was performed to determine the frequency of each drug in each class.
Results: Eight top-ranked drug classes were categorized from a list of 453 individual medications. Vitamins (30-40%) and anti-inflammatory (∼30%) drugs were the major categories for each cohort. Interestingly, 11% of drugs were proton pump inhibitors in non-demented patients, and this decreased by 8% in MCI, and 5% in AD. We found a reduced (8%) Lipitor prescriptions for AD patients compared MCI (11%) and non-demented (13%) patients. We are investigating the effects of these highly prescribed drugs on β-amyloid production/aggregation, cytotoxicity, plaque load, and tau phosphorylation in vitro and in vivo using cell culture and AD mouse models. Conclusion: While the effects of routinely prescribed drugs on AD pathology are not well known, we found reduced vitamins, proton pump inhibitors, and Lipitor in the medication profiles of AD patients compared to the non-AD population.
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Relationship Between Obesity and Triple-Negative Breast Cancer: A Retrospective Study
Mariam Aoun, Anna Jahshan, Nayana Dekhne, and Varna Taranikanti
Publication Date: 5-2-2022
INTRODUCTION
Several research studies have identified a positive correlation between obesity and specific receptor statuses in breast cancer, including ER-positive, PR-positive, and HER2-positive breast cancers. However, triple-negative breast cancer (TNBC) in particular has not been studied in relation to body mass index (BMI), which suggests that an analysis of triple-negative breast cancer and its relation to obesity is warranted. This study aims to analyze the association between triple-negative breast cancer and BMI through a retrospective analysis in order to further guide patient counseling about TNBC risk factors. -
Comparing Radiological characteristics of Neck Pain in Younger versus Older Patients: A retrospective analysis
Jnana Aditya Challa, Abdul Majid Khan, and Varna Taranikanti
Publication Date: 5-2-2022
INTRODUCTION
Neck pain commonly occurs during the fifth or sixth decade of life due to degenerative changes in the spine. With increased usage of digital technology from a very young age we hypothesized an earlier age of onset of these degenerative changes. There have been no recent epidemiologic studies that investigated difference in radiological changes seen in older versus younger patients presenting with neck pain. Hence, this study is undertaken to analyze the variability in radiological changes seen in the cervical vertebrae between older (>50) versus younger (≤50) patients presenting with the chief complaint of neck pain. -
ERAS vs Non-ERAS: A Hospital Performance Metrics Comparsion in Patients Undergoing Spinal Fusion
Richard W. Easton, Gregory Smith, Matthew Lipphardt, Nai-Wei Chen, Pestano Cecile, Hermeli Mateo, Austin Ahlgren, Brady Vibert, Andrew Sagante, and Susan Vander Beek
Publication Date: 5-2022
Hospital metrics are measures used to evaluate surgical quality. The goal is to improve standards of care (SOC). Hospital performance is made publicly available and has reimbursement ramifications.
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Prospective Qualitative Analysis of Minimally Invasive Repair of Pectus Excavatum
Timothy Elton, Diane Studzinski, Robert S. Morden, and Pavan Brahmamdam
Publication Date: 5-2-2022
INTRODUCTION
Pectus Excavatum is the most common chest wall deformity and is frequently corrected with the Nuss procedure. Although this procedure has existed for several decades, new strategies are being adapted to reduce complications and improve efficiency. The aim of this study is to perform a qualitative review of the patient experience after minimally invasive repair of Pectus Excavatum. -
Prehospital Use of Ketamine in the Pediatric Population
Ashima Goyal, Revelle Gappy, Remle Crowe, John Frawley, Nai-Wei Chen, and Robert Swor
Publication Date: 1-2022
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Effect of SARS-COV2 on Adolescent PHQ-9 Screening Result
Anisah Hashmi, Aimee Pollak, Leah Ludwig, Kerry P. Mychaliska, Mara Rubenstein, Olufunke Adeyemo, Stacey Shubeck, Liu Qu, and Mary Coffey
Publication Date: 5-2-2022
INTRODUCTION
The SARS-COV2 pandemic created numerous stressors for adolescents including financial insecurities, family illness or death, home schooling, discontinuation of group activities, and decreased peer interaction. Prior studies have shown an increased risk for self-reported depression symptoms in pediatric patients following traumatic events. The purpose of this study is to compare rates of newly diagnosed depression in adolescents and self-reported depression symptoms prior to and during the pandemic. -
Relationship Between Smoking and Triple-Negative Breast Cancer: A Retrospective Analysis
Anna Jahshan, Mariam Aoun, Nayana Dekhne, and Varna Taranikanti
Publication Date: 5-2-2022
INTRODUCTION
Breast cancer is currently the most common cancer by incidence among women in the United States with high mortality. Compared to other specific types, triple-negative breast cancer (TNBC) is considered to be an aggressive cancer with poor prognosis. Hence, it is important to study the risk factors associated with it. Smoking has been implicated in many cancers, including breast cancer. However, there is no evidence in literature that has shown a relationship between smoking and a specific type of breast cancer. The goal of this study is to analyze the relationship between smoking and TNBC so that we may improve the understanding of the risk factors related to this type of breast cancer. -
Clearance of the Cervical Spine in Obtunded Pediatric Blunt Trauma Patients: Quality Assessment of an Existing Clearance Pathway
Rachel Kalthoff, Elizabeth Boudiab, Diane Studzinski, Nathan Novotny, Pavan Brahmamdam, and Begum Akay
Publication Date: 5-2-2022
INTRODUCTION
Obtunded patients following blunt trauma need clearance of the cervical spine (c-spine) that cannot depend on a clinical exam. Our center’s current pediatric c-spine evaluation pathway includes both Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). The objective of this study was to review our use of both CT and MRI for obtunded pediatric trauma patients to assess the quality of our pathway and utility of MRI. -
Perioperative Antibiotic Use in Neonatal Surgery
Lior Kopel, Patrick Karabon, Nathan Novotny, Begum Akay, and Pavan Brahmamdam
Publication Date: 5-2-2022
INTRODUCTION
The ideal duration of perioperative antibiotic prophylaxis to prevent surgical site infection (SSI) in neonates is undetermined. The aim of this study is to evaluate the association between the duration of perioperative antibiotics and SSIs in the neonatal surgical population. -
Radioactive iodine therapy (RAIT) in N1 papillary thyroid cancer: Are we overtreating?
Elizabeth Odil, Jordan Reilly, Fionna Sun, Diane Studzinski, Rose E. Callahan, and Sapna Nagar
Publication Date: 4-28-2022
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Functional Lung Segmentation from Computed Tomography Images using Deep Learning
Duyen M. Quach, Evan Porter, and Thomas M. Guerrero
Publication Date: 5-2-2022
INTRODUCTION
Functional avoidance treatment planning allows radiation oncologists to intentionally minimize radiation dose to higher-functioning lung areas while favoring radiation dose towards lower-functioning regions. This treatment planning method has been shown to reduce pulmonary toxicity for patients receiving radiation therapy. Functional lung information, traditionally ventilation or perfusion SPECT scans, is required to plan for functional avoidance. -
Acute Post-Operative Pain Following Anterior Cruciate Ligament Reconstruction: A comparison of Patellar Tendon vs Hamstring Autograft
Dustin J Randall, Denise Koueiter, Brandon Luczak, and Kyle Anderson
Publication Date: 5-2-2022
INTRODUCTION
Choosing between a bone-patellar tendon-bone (BTB) or hamstring tendon (HS) graft for primary anterior cruciate ligament (ACL) reconstruction has long been a topic of debate and discrepancy in orthopaedic literature, with many factors contributing to the decision process. The purpose of this study is to analyze acute post-operative pain scores of patients who underwent ACL reconstruction and compare the results between BTB autograft and the HS autograft techniques. -
Spontaneous Pneumomediastinum in Children is Not Associated with Esophageal Perforation
Kevin Roby, Catherine Barkach, Diane Studzinski, Nathan Novotny, Begum Akay, and Pavan Brahmamdam
Publication Date: 5-2-2022
INTRODUCTION
We hypothesize that esophageal perforation is not a common etiology for spontaneous pneumomediastinum (SPM), and that SPM is a self-limited disease not requiring routine admission. -
Urinary cytokines as potential biomarkers of mild cognitive impairment and Alzheimer’s disease: a pilot study
Nazia Saiyed, Ali Yilmaz, Sangeetha Vishweswariah, Sarah Bartolone, Tammy Osentoski, Stacey Ruff, Amita Pai, Michael Maddens, Khaled Imam, and Stewart F. Graham
Publication Date: 10-21-2022
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