Perineural Spread of Head and Neck Neoplasms Along Cranial Nerves

Authors

Megan Moore, Corewell Health Resident
Carol Lima, Corewell Health Resident
Anant Krishnan, Corewell Health
Mehdy Haidar, Corewell Health Resident
Sylvia Kashat, Oakland University William Beaumont School of Medicine Medical Student
Maxwell Li, Oakland University William Beaumont School of Medicine Medical Student
Samir Noujaim, Corewell Health

Document Type

Article

Publication Date

9-30-2024

Publication Title

Contemporary Diagnostic Radiology

Abstract

Perineural tumor growth involves tumors infiltrating local nerves, either through perineural tumor invasion or perineural tumor spread (PNS). Knowledge of cranial nerves and skull base anatomy is essential for identifying affected nerve pathways. Various cancers like squamous cell carcinoma, adenoid cystic carcinoma, and lymphoma, among others, can progress with PNS. Imaging techniques such as MRI and CT are pivotal for detecting PNS and its signs and symptoms. PNS typically indicates a worse prognosis, increased recurrence rate, and lower survival. Understanding PNS patterns, behaviors, and imaging characteristics is vital for accurate diagnosis and optimal treatment planning in patients with head and neck tumors.

Volume

47

Issue

20

First Page

1

Last Page

8

Recommended Citation

Moore M, Lima C, Krishnan A, Haidar M, Kashat S, Li M, et al. [Noujaim S]. Perineural spread of head and neck neoplasms along cranial nerves. Contemporary Diagnostic Radiology. 2024 Sep 30;47(20):1-8. doi:10.1097/01.CDR.0001051064.15765.66

DOI

10.1097/01.CDR.0001051064.15765.66