Responsive Neurostimulation (RNS) of the Centromedian Nucleus (CMN) of the Thalamus for the Treatment of Drug Resistant Idiopathic Generalized Epilepsy (IGE)

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Authors

Angelique Manasseh, Corewell Health Resident
Hannah Guider, Corewell Health Resident
Brooklynn Bondy, Corewell Health Resident
Sanjay Patra, Corewell Health West
David Burdette, Corewell Health West
M. Ayman Haykal, Corewell Health West
Nour Baki, Corewell Health
Ashleigh Terrell, Corewell Health
Michael Staudt, Corewell Health
Christopher Parres, Corewell Health
Andrew Zillgitt, Corewell Health

Description

Idiopathic generalized epilepsy (IGE) accounts for nearly 1/3 of all epilepsies.

Approximately 20-30% of people with IGE are refractory to adequate anti-seizure medication trials.

RNS implantation is a unique closed-loop neuromodulation therapy, and case reports as well as case series have demonstrated improved seizure control in patients with drug resistant IGE.

More recently, targeting the centromedian nucleus of the thalamus with RNS has been explored as a potential surgical treatment option for patients with drug resistant IGE.

Publication Date

5-9-2024

Disciplines

Neurology | Neurosurgery | Nursing

Recommended Citation

Manasseh A, Guider H, Bondy B, Patra S, Burdette D, Haykal MA et al [Baki N, Terrell A, Staudt M, Parres C, Zillgitt A] Responsive neurostimulation (rns) of the centromedian nucleus (cmn) of the thalamus for the treatment of drug resistant idiopathic generalized epilepsy (ige). Presented at Corewell Health Hospital Farmington Hills 2024 Alvin Yarrows Research Day; 2024 May 9; Farmington Hills, MI.

Comments

2024 Alvin Yarrows Research Day at Corewell Health Hospital Farmington Hills, Farmington Hills, MI, May 9, 2024.