Impact of Pulmonary Hypertension on Catheter Ablation for Atrial Fibrillation
Document Type
Conference Proceeding
Publication Date
5-2024
Publication Title
Heart Rhythm
Abstract
Background: Patients with atrial fibrillation (AF) and concomitant pulmonary hypertension (pHTN) have an increased risk of morbidity and mortality. However, the outcomes of catheter ablation in this cohort are unclear. Objective: We compared the outcomes of catheter ablation in patients with AF and underlying pHTN to those without pHTN. Methods: The National Readmission Database (NRD) from 2016-2020 was used to identify patients with AF and pHTN who underwent AF ablation using appropriate ICD-10 codes. The primary outcome was AF readmission at 11 months. Secondary outcomes were heart failure (HF) readmissions, readmission related mortality, and all-cause re-admissions at 11 months. Cox proportional hazard regression was used to compare the outcomes between pHTN vs. no pHTN, and hazard ratios were calculated. Results: Out of 112,174 patients with AF who had an ablation, 10,144 had associated pHTN. On propensity-matched outcomes comparing with vs. without pHTN groups, there was no statistical difference in the primary endpoint of AF readmission [Hazard Ratio (HR) 5 0.93 (0.82-1.05); p50.25]. Secondary outcomes showed increased HF readmissions [HR 5 1.34 (1.25-1.45); p,0.0001], Readmission mortality [HR 5 1.22 (1.04-1.43); p50.01], and All-cause readmission [HR 5 1.08 (1.02-1.15); p50.008] among patients receiving AF Ablation with pHTN when compared to patients without pHTN at 11 months follow-up. Conclusion: Patients with pHTN undergoing catheter ablation for AF have an increased risk of HF readmissions, readmissions related mortality, and all-cause readmissions as compared to those without pHTN.
Volume
21
Issue
5S
First Page
S446
Last Page
S447
Recommended Citation
Patel H, Sheth A, Pandya K, Patel B, Nair AV, Ul Abideen Asad Z, et al. [Mehta N]. Impact of pulmonary hypertension on catheter ablation for atrial fibrillation. Heart Rhythm. 2024 May;21(5S):S446-S447. doi:10.1016/j.hrthm.2024.03.1182
DOI
10.1016/j.hrthm.2024.03.1182
Comments
Heart Rhythm Society Annual Meeting, May 16-29, 2024, Boston, MA