Low Energy Shock Wave Therapy Inhibits Inflammatory Molecules and Suppresses Prostatic Pain and Hypersensitivity in a Capsaicin Induced Prostatitis Model in Rats.

Authors

Hung-Jen Wang
Pradeep Tyagi
Yu-Ming Chen
Michael B Chancellor, Beaumont Health
Yao-Chi Chuang

Document Type

Article

Publication Date

9-26-2019

Publication Title

Int J Mol Sci

Abstract

The effect of low energy shock wave (LESW) therapy on the changes of inflammatory molecules and pain reaction was studied in a capsaicin (10 mM, 0.1 cc) induced prostatitis model in rats. Intraprostatic capsaicin injection induced a pain reaction, including closing of the eyes, hypolocomotion, and tactile allodynia, which effects were ameliorated by LESW treatment. LESW therapy (2Hz, energy flux density of 0.12 mJ/mm

Volume

20

Issue

19

First Page

4777

Recommended Citation

Wang HJ, Tyagi P, Chen YM, Chancellor MB, Chuang YC. Low Energy Shock Wave Therapy Inhibits Inflammatory Molecules and Suppresses Prostatic Pain and Hypersensitivity in a Capsaicin Induced Prostatitis Model in Rats. Int J Mol Sci. 2019 Sep 26;20(19):4777. doi: 10.3390/ijms20194777. PMID: 31561455; PMCID: PMC6801724.

DOI

10.3390/ijms20194777

ISSN

1422-0067

PubMed ID

31561455