Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report.

Document Type

Article

Publication Date

9-25-2023

Publication Title

Urology case reports

Abstract

A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3-4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation.

Volume

51

First Page

102575

DOI

10.1016/j.eucr.2023.102575

ISSN

2214-4420

PubMed ID

37829494

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