A rare case of pure N4-acetyl-sulfamethoxazole nephrolithiasis associated with trimethoprim-sulfamethoxazole treatment of pulmonary nocardiosis.
Document Type
Article
Publication Date
8-3-2022
Publication Title
Urology Case Reports
Abstract
Trimethoprim-Sulfamethoxazole is a commonly used antibiotic for treatment of urinary tract infections, but also used to treat less common conditions such as pulmonary nocardiosis. N4-acetyl-sulfamethoxazole is the main active metabolite of Sulfamethoxazole. Pure stones of this compound are very rare with only a few cases documented in the literature. Here we present a case of a patient treated with long term trimethoprim-sulfamethoxazole therapy for pulmonary nocardiosis who developed pure N4-acetyl-sulfamethoxazole nephrolithiasis resulting in upper tract obstruction. This report provides an additional data point for this unique calculus etiology.
Volume
45
First Page
102179
Last Page
102179
Recommended Citation
Shanholtzer A, Geisenhoff A, Shah M, Shetty S. A rare case of pure N4-acetyl-sulfamethoxazole nephrolithiasis associated with trimethoprim-sulfamethoxazole treatment of pulmonary nocardiosis. Urol Case Rep. 2022 Aug 3;45:102179. doi: 10.1016/j.eucr.2022.102179. PMID: 35991217.
DOI
10.1016/j.eucr.2022.102179
ISSN
2214-4420
PubMed ID
35991217