Document Type

Conference Proceeding

Publication Date

5-2021

Publication Title

Annals of Surgical Oncology

Abstract

Background/Objective: Breast cancer overall survival rate in Black American (BA) women is lower compared to White American (WA) women. Inflammatory breast cancer (IBC) is a rare but aggressive subtype of breast cancer that is found at higher incidence in the BA patients. The objective of this study was to evaluate trends and identify factors that contribute to racial disparities in outcomes of women with IBC. Methods: The National Cancer Database (NCDB) was used to evaluate patients with Stage III IBC from 2004 to 2014. Patient demographics, tumor characteristics, treatments and survival trends were stratified by race for comparison. Results: A total of 10,160 cases were selected with 85% (n=8,591) WA patients and 15% (n=1,569) BA patients. Median follow-up was 58 months. BA patients were significantly younger at diagnosis with mean age of 54 years (SD: 13) compared to WA at mean age of 57 (SD: 13) (p80%) did not undergo both radiation and chemotherapies. Out of the small group of patients who received chemo and radiation, BA patients had slightly higher rates (17% vs 15%, p=0.006). A significant difference in overall mortality showed that BA patients had 39% greater hazard ratio compared to WA. (95% CI: 1.28, 1.51); p=< 0.001). Conclusions: BA women were younger age at diagnosis with higher tumor grades, suggesting more aggressive IBC type compared to WA women. BA patients had lower survival despite having higher rates of trimodal therapy. Disparity in survival may relate to underlying tumor biology and socioeconomic factors, access to insurance, income, and education levels.

Volume

28

Issue

Supplement 2

First Page

S290

Last Page

S292

Comments

The American Society of Breast Surgeons Official Proceedings, Volume XXII 2021 Annual Meeting Scientific Session Abstract, May, 2021.

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