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The COVID-19 pandemic has emphasized that the virus can cause multi-organ complications, especially in patients with pre-existing conditions such as type-2 diabetes mellitus (T2DM), who are at higher risk for poor outcomes. Some patients may also develop T2DM post-infection due to the virus's effects on insulin secretion and blood glucose regulation. Glycated hemoglobin (HbA1c) is a useful tool for assessing blood glucose levels over time, diagnosing diabetes and monitoring disease management. Elevated levels of HbA1c have been linked to diabetic nephropathy (DN) and chronic kidney disease (CKD), both of which are potential complications of COVID-19 infection. This study aims to investigate the development of CKD in patients with varying HbA1c levels, and other comorbidities after SARS-CoV-2 infection, hypothesizing that COVID-19 may accelerate the development of CKD in at-risk patients with higher levels of HbA1c.
Translational Medical Research
Leon E, John J, Ludka N, Homayouni R. A retrospective study on the incidence of CKD diagnosis post COVID-19 infection with variations in glycemic control . Poster presented at: Oakland University William Beaumont School of Medicine Embark Capstone Colloquium; 2023 May; Rochester Hills, MI.