Accuracy and uniformity of the nomenclature of biogenic amines and polyamines in metabolomics studies: A preliminary study.

Document Type

Article

Publication Date

5-2021

Publication Title

Biochem Mol Biol Educ

Abstract

Metabolomics is one of the newest areas in biochemistry dedicated to investigating small biomolecules in biofluids, tissues, and cells. Cutting edge instruments used in metabolomics studies make it possible to identify thousands of biomolecules and determine their interactions with biological networks. This tremendous area has increased the significance of accurate chemical nomenclature of compounds. Therefore, the classification of the organic molecules has become one of the most important issues in the field. Biogenic amines are nitrogenous compounds of low molecular weight formed by the decarboxylation of amino acids or by the amination and the transamination of aldehydes and ketones during normal metabolic processes. This letter covers the topic of nomenclature with respect to the current usage of biogenic amines in scientific literature. We use metabolomics as an example of field reporting data on trace levels of molecules that may be miscategorized in primary literature. We suggest that the incorrect classification of molecules will influence science education adversely because resources used for teaching are drawn from primary literature references that may contain errors.

Volume

49

Issue

3

First Page

441

Last Page

445

DOI

10.1002/bmb.21497

ISSN

1539-3429

PubMed ID

33682332

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