2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic AHR-mediated differential gene expression

Authors

Warren J Sink
Russell Fling
Ali Yilmaz, Corewell Health
Rance Nault
Delanie Goniwiecha
Jack R Harkema
Stewart F. Graham, Corewell Health
Timothy Zacharewski

Document Type

Article

Publication Date

10-25-2024

Publication Title

bioRxiv

Abstract

Epidemiological evidence suggests an association between dioxin and dioxin-like compound (DLC) exposure and human liver disease. The prototypical DLC, 2,3,7,8-tetrachlorodibenzo-

Recommended Citation

Sink WJ, Fling R, Yilmaz A, Nault R, Goniwiecha D, Harkema JR, et al [Graham SF] 2,3,7,8-Tetrachlorodibenzo-p-dioxin (tcdd) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic ahr-mediated differential gene expression. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619714. doi: 10.1101/2024.10.22.619714. PMID: 39484576

DOI

10.1101/2024.10.22.619714

ISSN

2692-8205

PubMed ID

39484576