The impact of socioeconomic status on overall survival in patients at a radiation oncology center: A retrospective study

Authors

Bailey Loving, Corewell Health Resident
Ronald Levitin, Corewell Health
Lihua `. Qu, Corewell Health
Hong Ye, Corewell Health
Elizabeth Rutka, Corewell Health
John M. Robertson, Corewell Health

Document Type

Conference Proceeding

Publication Date

9-30-2024

Publication Title

Journal of Clinical Oncology

Abstract

Background:There are few reports examining the impact of socioeconomic status (SES), as indicated by the Area Deprivation Index (ADI), on overall survival (OS) in radiation oncology patients, making this an important area of investigation. This study aims to investigate the influence of ADI on OS in radiation oncology patients, while controlling for stage and other relevant variables.Methods:This retrospective study analyzed data from radiation oncology patients treated at a large multi-site single-institution center from October 2006 to January 2024. Demographic and treatment information, including age, gender, race, insurance status, comorbidity index (CCI), mental health disorders (MHD), treatment intent, cancer type, and stage, were collected. The ADI was used to measure SES and was gathered from the Neighborhood Atlas. Kaplan-Meier curves were generated for all patients, with separate curves for different cancer types. The impact of demographic, clinical, and socioeconomic factors on OS was assessed using a Cox proportional hazards multivariable (MVA) logistic regression analysis. The model was stratified by treatment intent, cancer type, stage, insurance status, and CCI.Results:In this comprehensive analysis of 7343 patients, the median follow-up was 12.00 months (IQR: 1.8–36.82). Most patients were breast cancer (30.2%), over 65 years old (60.5%), and had an ADI below the mean (55.5%), indicating lower socioeconomic disadvantage. Kaplan-Meier analysis showed that 5-year OS rates were significantly lower for the fourth quartile ADI group (85.1%) compared to the first quartile ADI group (94.0%) (p

Volume

20

Issue

10

First Page

147

Recommended Citation

Loving B, Levitin R, Qu L, Ye H, Rutka, Robertson J. The impact of socioeconomic status on overall survival in patients at a radiation oncology center: A retrospective study. J Clin Oncol. 2024 Sept 30;20(10):147. doi: 10.1200/OP.2024.20.10_suppl.147

Comments

The 2024 ASCO Quality Care Symposium , September 27-28, 2024, San Francisco, CA

DOI

10.1200/OP.2024.20.10_suppl.147