Redefine the Role of Spot-Scanning Proton Beam Therapy for the Single Brain Metastasis Stereotactic Radiosurgery.
Frontiers in oncology
PURPOSE: To explore the role of using Pencil Beam Scanning (PBS) proton beam therapy in single lesion brain stereotactic radiosurgery (SRS), we developed and validated a dosimetric in silico model to assist in the selection of an optimal treatment approach among the conventional Volumetric Modulated Arc Therapy (VMAT), Intensity Modulated Proton Therapy (IMPT) and Spot-scanning Proton Arc (SPArc).
MATERIAL AND METHODS: A patient's head CT data set was used as an in
RESULTS: The study showed that SPArc has a dosimetric advantage in the V
CONCLUSION: The study demonstrated the feasibility of using Proton beam therapy for single brain metastasis patients utilizing the SPArc technique. At the current stage of technological development, VMAT remains the current standard modality of choice for single lesion brain SRS. The
Chang S, Liu G, Zhao L, Zheng W, Yan D, Chen P, et al. [Li X, Deraniyagala R, Stevens C, Grills I, Chinnaiyan P, Li X, Ding X] Redefine the role of spot-scanning proton beam therapy for the single brain metastasis stereotactic radiosurgery. Front Oncol. 2022 May 19;12:804036. doi: 10.3389/fonc.2022.804036. PMID: 35664795.