Effective Pediatric Blood Management in Craniosynostosis Surgery: A Long-Term Update.

Document Type

Article

Publication Date

10-11-2024

Publication Title

The Journal of craniofacial surgery

Abstract

BACKGROUND: Blood transfusion is common in cranial vault surgery, and protocolized efforts to minimize transfusion have been reported in recent years. This study assesses the long term, prospective outcomes of a pediatric blood management protocol for the cranial vault reconstruction (CVR) population.

MATERIALS AND METHODS: Data from a retrospective control cohort and a prospective cohort employing a protocol for preoperative hematologic optimization of patients undergoing CVR from January 2015 to October 2023 was reviewed. Preoperative hemoglobin (Hgb) determined the preoperative protocol. Intraoperative tranexamic acid (TXA) and/or aminocaproic acid, cell-saver technology, and postoperative iron or erythropoietin alfa supplementation were also used in the protocol. For statistical analysis, P

RESULTS: The cohort consisted of 194 successive patients (20 control and 174 treatment). Age, sex, and weight were not significantly different between groups. Mean postoperative Hgb was significantly higher in the control group (P

CONCLUSION: Efforts to optimize blood management in the CVR population are critical. This prospective study represents a robust and reproducible protocol for pediatric blood management with significant reductions in transfusion requirements.

DOI

10.1097/SCS.0000000000010682

ISSN

1536-3732

PubMed ID

39392624

Link to Full Text

Share

COinS