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  Impact of Continuous Infusion Ketamine as Sedation on Concomitant Opioid and Sedative Requirements in Mechanically Ventilated COVID-19 Patients

  Gabrielle R. Bradley, Megan Cadiz, and Allycia Natavio

  Publication Date: 12-7-2022

  Characterize the impact of continuous infusion ketamine (CIK) on concomitant opioid and sedative requirements in mechanically ventilated COVID-19 patients

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  Levetiracetam for Seizure Prophylaxis in Spontaneous Intracerebral Hemorrhage

  Alanah Bratley, Krystal Commons, and Allycia Natavio

  Publication Date: 12-7-2022

  Characterize the use of levetiracetam for early seizure prophylaxis in patients with sICH

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  Pharmacist-Provided Educational Intervention and its Impact on Medical Resident Knowledge and Comfort Level with Continuous Glucose Monitors (CGMs)

  Chelsea Dezfuli, Sarah Muench, and Colleen Lauster

  Publication Date: 12-7-2022

  Continuous glucose monitors (CGMs) have become an integral component of diabetes care

  American Diabetes Association now recommends that CGMs be offered to all patients on insulin who can use the device safely

  Integrating CGMs into clinical practice can be challenging for several reasons: – Data overload – Cost – Need for education on data interpretation

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  Evaluation of Antimicrobial Prophylaxis in Spine Surgery within an Enhanced Recovery Program at a Large Community Teaching Hospital

  Sabrina DiPietro, Klea Noskey, Richard Zoltowski, Tania Saeed, and Sapna Shah

  Publication Date: 12-7-2022

  The risk of surgical site infections post spine surgery is 0% to 18%.1

  • American Society of Health System Pharmacists (ASHP) and Enhanced Recovery After Surgery (ERAS) Society guidelines recommend using an agent with activity against the most common surgical site pathogens including Staphylococcus aureus. 2,3

  • The preferred agent is cefazolin 2 grams intravenous (IV) (3 grams if patient weighs ≥120 kilograms [kg]) administered 30 minutes prior to skin incision and re-dosed every four hours intraoperatively.2,3

  • In the case of a cephalosporin allergy, clindamycin 900 milligrams (mg) IV or vancomycin 15 mg/kg IV are recommended alternatives.2,3

  • Due to lack of appropriate documentation of allergies in the electronic medical record (EMR), alternative antimicrobials are often prescribed.

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  Impact of Soy-Based Versus Composite Lipid Emulsion (Soybean, Medium Chain Triglycerides, Olive and Fish Oil) in Critically Ill Patients

  Sandra Kless, Lisa Hall Zimmerman, and Olaf Kroneman

  Publication Date: 3-2022

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  Evaluation of Antibiotic Selection and Duration in Patients with Non-Severe Community Acquired Pneumonia

  Emily Reich, Sandra Hartnagle, Jennifer Pilotto, Heidi Klotz, and Ryan Herc

  Publication Date: 12-7-2022

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  Evaluation of Safety Outcomes of Two Hydrocortisone Dosing Regimens in Patients in Septic Shock

  Alexandra Rola, Joshua Wirtz, Daniel Kalaj, Vasil Rrushi, and Megan Cadiz

  Publication Date: 12-7-2022

  • Steroids are used in shock to minimize the impact of shock-induced dysregulation of inflammatory response – Hydrocortisone is preferred for its activity as a glucocorticoid and a mineralocorticoid • Available data on the use of hydrocortisone shows mixed benefit – Data to guide dosing is limited, use of 100 mg IV every 8 hours may have benefit over 50 mg IV every 6 hours • Use of steroids has been associated with potential risks, including gastrointestinal bleeding, hyperglycemia, hypernatremia, superinfection, etc.

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  Ertapenem Versus Meropenem for the Treatment of ESBL-Producing Enterobacterales Bacteremia in Critically Ill Patients

  Sydney VanDorf, Prakash Shah, Chad Richardson, and Christine Yost

  Publication Date: 12-7-2022

  The purpose of this study is to evaluate clinical outcomes for critically ill patients receiving ertapenem or meropenem for ESBL-producing Enterobacterales bacteremia.

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  Safety Evaluation of Intravenous Heparin Protocol Following Alteplase Treatment in Patients with Suspected or Confirmed Pulmonary Embolism

  Erika Waldsmith, Lisa Hall Zimmerman, and Claudia Hanni

  Publication Date: 12-7-2022