"Candidemia Surveillance and Impact on Non-Neutropenic Critically Ill P" by Lisa Zimmerman, Heather Dolman et al.
 

Candidemia Surveillance and Impact on Non-Neutropenic Critically Ill Patients.

Document Type

Article

Publication Date

11-6-2024

Publication Title

Cureus

Abstract

BACKGROUND: Candidemia is a common pathogen in critically ill patients and has a significant negative impact on morbidity and mortality. Risk factors linked with candidemia are reported in the literature. We evaluated the risk factors associated with candidemia in critically ill patients on mortality rates, including the impact of delayed or inadequate antifungal therapy (IAAT).

METHODS: This retrospective study evaluated non-neutropenic critically ill adult patients with candidemia for six consecutive years. Antifungal therapy was evaluated for the following: the correct dose based on the

RESULTS: In the 91 critically ill patients evaluated with documented candidemia, the mean age was 57±16 years, the mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 25±9, and the overall mortality rate was 38%. Patients with the following risk factors for candidemia had an increased mortality: use of mechanical ventilation (35 (100%), p

CONCLUSIONS: In critically ill patients with risk factors associated with candidemia, AAT is important when candidemia is suspected. This study found that

Volume

16

Issue

11

First Page

e73155

DOI

10.7759/cureus.73155

ISSN

2168-8184

PubMed ID

39650902

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