Use of Colony-Stimulating Factors in Patients With Systemic Lupus Erythematosus.

Document Type

Article

Publication Date

6-2023

Publication Title

Journal of pharmacy practice

Abstract

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that commonly manifests as cutaneous rashes, renal disease, gastrointestinal dysfunction, and cytopenia. Hematological anomalies are frequently associated with drug-induced toxicity in SLE patients. Colony-stimulating factors have been used to treat drug-induced cytopenia in past case reports; however, evidence suggests that colony-stimulating factors can exacerbate autoimmune disorders, including SLE. This case report presents two patients with SLE exacerbations after colony-stimulating factor administration. The first case is a young male with SLE who developed pancytopenia with a white blood cell count (WBC) of 1 × 10

Volume

36

Issue

3

First Page

719

Last Page

724

DOI

10.1177/08971900211053268

ISSN

1531-1937

PubMed ID

34748466

Link to Full Text

Share

COinS