Management of severe hyperbilirubinemia in the cholestatic neonate: a review and an approach.

Authors

Jon F Watchko
M Jeffrey Maisels, Beaumont Health

Document Type

Article

Publication Date

6-1-2022

Publication Title

Journal of perinatology : official journal of the California Perinatal Association

Abstract

A review of the literature demonstrates that severe total hyperbilirubinemia (total serum bilirubin ≥ 20 mg/dL [340 µmol/L]) in some cholestatic term (≥37 weeks) and late-preterm (≥340/7-366/7 weeks) gestation neonates poses a risk for bilirubin-induced brain damage. When the direct bilirubin fraction is

Volume

42

Issue

6

First Page

695

Last Page

701

Recommended Citation

Watchko JF, Maisels MJ. Management of severe hyperbilirubinemia in the cholestatic neonate: a review and an approach. J Perinatol. 2022 Jun;42(6):695-701. doi: 10.1038/s41372-022-01330-8. PMID: 35145210.

DOI

10.1038/s41372-022-01330-8

ISSN

1476-5543

PubMed ID

35145210