Primary Parotid Tumor Thrombosis: Immunohistologic Features and Awareness of Metastatic Potential.
Document Type
Article
Publication Date
7-4-2021
Publication Title
Cureus
Abstract
Tumor thrombosis is a poor prognostic feature and an exceptionally rare occurrence in salivary gland malignancies. We present a case of primary parotid myoepithelial carcinoma (MC) with tumor thrombosis in the external jugular vein (EJV). An 82-year-old man presented with a right-sided facial mass. MRI with and without gadolinium demonstrated a mass of the right parotid gland with a filling defect of the right EJV. The patient underwent right parotidectomy and selective neck dissection. Tumor thrombosis was found intraoperatively within the EJV. Final pathology demonstrated a poorly differentiated MC. Adjuvant radiation therapy without concurrent systemic therapy was administered. Three months later, restaging positron emission tomography (PET) with CT revealed numerous bilateral pulmonary nodules with biopsy, demonstrating poorly differentiated MC without locoregional relapse. Given that primary parotid tumor thrombosis is associated with a poor prognosis, the use of early systemic therapy should be investigated.
Volume
13
Issue
7
First Page
16174
Recommended Citation
Dekhou A, Rehman R, Parzen JS, Quinn TJ, Zhang PL, Rontal M, Noujaim S, Tapia M, Deraniyagala R. Primary Parotid Tumor Thrombosis: Immunohistologic Features and Awareness of Metastatic Potential. Cureus. 2021 Jul 4;13(7):e16174. doi: 10.7759/cureus.16174. PMID: 34367782; PMCID: PMC8336355.
DOI
10.7759/cureus.16174
ISSN
2168-8184
PubMed ID
34367782