Peripheral Retinal Angiographic Findings in Macular Telangiectasis Type 2.
Retina (Philadelphia, Pa.)
PURPOSE: To evaluate the retinal periphery in patients with idiopathic juxtafoveal telangiectasis or macular telangiectasis Type 2 (MacTel2), using widefield fluorescein angiography.
METHODS: Single-center, retrospective, observational case series of 50 eyes of 50 patients with MacTel2 and 50 eyes of 50 age-matched controls.
RESULTS: Thirty-seven eyes in the MacTel2 group (74%) showed peripheral capillary nonperfusion or dropout, compared with 37 eyes in the control group (74%, P = 1.0). Morphologically, the MacTel2 group trended toward having a higher proportion of pruning-type capillary dropout (44%) compared with controls (28%), but this was not statistically significant (P = 0.12). Patients with MacTel2 had a higher incidence of microaneurysms compared with controls (MacTel2 56%; controls 42%; P = 0.048), independent of age or systemic risk factors. There was no difference in the incidence of venous-venous shunts (MacTel2 10%; controls 10%; P = 1.0), arteriovenous shunts (MacTel2 14%; controls 18%; P = 0.60), venous tortuosity (MacTel2 60%; controls 66%; P = 0.58), or arterial tortuosity (MacTel2 54%; controls 68%; P = 0.20), which was mild in most cases.
CONCLUSION: We note a high incidence of peripheral vascular and retinal findings in both patients with MacTel2 and age-matched controls, using widefield fluorescein angiography. Patients with MacTel2 had significantly more microaneurysms, independent of age or other systemic risk factors.
Moysidis SN, Koulisis N, Rao P, Govindaraju VK, Gamsky S, Mahmoud TH, Randhawa S, Faia LJ, Wolfe JD, Drenser KA, Ruby AJ, Garretson BR, Hassan TS, Williams GA, Trese MT, Capone A Jr. Peripheral Retinal Angiographic Findings in Macular Telangiectasis Type 2. Retina. 2021 Mar 1;41(3):480-486. doi: 10.1097/IAE.0000000000002981. PMID: 32969983.