Peripheral Retinal Angiographic Findings in Macular Telangiectasis Type 2.

Authors

Stavros N Moysidis, Beaumont Health
Nicole Koulisis, Beaumont Health Resident
Prethy Rao, Beaumont Health Fellow
Viren K Govindaraju, Beaumont Health Resident
Samuel Gamsky, Oakland University William Beaumont School of Medicine Medical Student
Tamer H Mahmoud, Beaumont Health
Sandeep Randhawa, Beaumont Health
Lisa J Faia, Beaumont Health
Jeremy D Wolfe, Beaumont Health
Kimberly A Drenser, Beaumont Health
Alan J Ruby, Beaumont Health
Bruce R Garretson, Beaumont Health
Tarek S Hassan, Beaumont Health
George A Williams, Beaumont Health
Michael T Trese, Beaumont Health
Antonio Capone, Beaumont Health

Document Type

Article

Publication Date

3-1-2021

Publication Title

Retina (Philadelphia, Pa.)

Abstract

PURPOSE: To evaluate the retinal periphery in patients with idiopathic juxtafoveal telangiectasis or macular telangiectasis Type 2 (MacTel2), using widefield fluorescein angiography.

METHODS: Single-center, retrospective, observational case series of 50 eyes of 50 patients with MacTel2 and 50 eyes of 50 age-matched controls.

RESULTS: Thirty-seven eyes in the MacTel2 group (74%) showed peripheral capillary nonperfusion or dropout, compared with 37 eyes in the control group (74%, P = 1.0). Morphologically, the MacTel2 group trended toward having a higher proportion of pruning-type capillary dropout (44%) compared with controls (28%), but this was not statistically significant (P = 0.12). Patients with MacTel2 had a higher incidence of microaneurysms compared with controls (MacTel2 56%; controls 42%; P = 0.048), independent of age or systemic risk factors. There was no difference in the incidence of venous-venous shunts (MacTel2 10%; controls 10%; P = 1.0), arteriovenous shunts (MacTel2 14%; controls 18%; P = 0.60), venous tortuosity (MacTel2 60%; controls 66%; P = 0.58), or arterial tortuosity (MacTel2 54%; controls 68%; P = 0.20), which was mild in most cases.

CONCLUSION: We note a high incidence of peripheral vascular and retinal findings in both patients with MacTel2 and age-matched controls, using widefield fluorescein angiography. Patients with MacTel2 had significantly more microaneurysms, independent of age or other systemic risk factors.

Volume

41

Issue

3

First Page

480

Last Page

486

Recommended Citation

Moysidis SN, Koulisis N, Rao P, Govindaraju VK, Gamsky S, Mahmoud TH, Randhawa S, Faia LJ, Wolfe JD, Drenser KA, Ruby AJ, Garretson BR, Hassan TS, Williams GA, Trese MT, Capone A Jr. Peripheral Retinal Angiographic Findings in Macular Telangiectasis Type 2. Retina. 2021 Mar 1;41(3):480-486. doi: 10.1097/IAE.0000000000002981. PMID: 32969983.

DOI

10.1097/IAE.0000000000002981

ISSN

1539-2864

PubMed ID

32969983