"A Case of Uveal Melanoma Masquerading as Choroidal Lymphoma." by Saleh Sahal, Stepanian Rima et al.
 

A Case of Uveal Melanoma Masquerading as Choroidal Lymphoma.

Document Type

Article

Publication Date

2-14-2025

Publication Title

Retin Cases Brief Rep

Abstract

PURPOSE: To present a case of uveal melanoma masquerading as choroidal lymphoma.

METHODS: A retrospective case report in which medical and imaging records, including fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein angiography, and ultrasonography were reviewed.

RESULTS: A 77-year-old woman presented with decreased vision was found to have a diffuse, shallow, yellow choroidal mass associated with RPE pigmentary changes and exudative detachment in her right eye. Multi-modal imaging demonstrated thickened choroid with a "lumpy-bumpy" appearance on OCT, "leopard-spotting" on fundus autofluorescence, and a shallow "table-top" configuration on B scan. Systemic workup was unremarkable. The patient elected to undergo treatment with low-dose external beam radiation for presumed choroidal lymphoma. There was no response to radiation prompting retinochoroidal biopsy, which revealed spindle-cell uveal melanoma and resulted in enucleation.

CONCLUSION: We present a case of uveal melanoma masquerading as choroidal lymphoma. This case highlights that uveal melanoma can rarely masquerade as other entities, including uveal lymphoma.

DOI

10.1097/ICB.0000000000001738

ISSN

1937-1578

PubMed ID

39983096

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