Bilateral horizontal gaze palsy, esotropia, and diplopia secondary to anti-Hu paraneoplastic syndrome.
Document Type
Article
Publication Date
4-18-2025
Publication Title
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus
Abstract
Paraneoplastic syndrome (PNS) refers to complications of cancer that arise from remote effects via immune-mediated mechanisms rather than direct effects from a neoplasm or metastases. Clinical presentations can be highly variable and may include optic neuropathy, opsoclonus, and neuromuscular junction disease. We report the case of a 40-year-old man with PNS who presented with complete bilateral horizontal gaze palsy, bilateral esotropia, and diplopia. He underwent bilateral full-tendon transpositions of the vertical rectus muscles to the lateral rectus muscle, with lateral augmentation sutures on the more severely affected left eye. The esotropia and diplopia had largely resolved by postoperative week 6, but horizontal movements were still absent.
First Page
104209
Recommended Citation
Jabara J, Rao R. Bilateral horizontal gaze palsy, esotropia, and diplopia secondary to anti-Hu paraneoplastic syndrome. J AAPOS. 2025 Apr 18:104209. doi: 10.1016/j.jaapos.2025.104209. Epub ahead of print. PMID: 40254244.
DOI
10.1016/j.jaapos.2025.104209
ISSN
1528-3933
PubMed ID
40254244
