"Combined Amniotic Membrane Graft and Autologous Retinal Transplant for" by Zujaja Tauqeer, Jong Park et al.
 

Combined Amniotic Membrane Graft and Autologous Retinal Transplant for Repair of Refractory Chronic Myopic Macular Holes

Document Type

Article

Publication Date

5-2-2024

Publication Title

Retinal Cases & Brief Reports

Abstract

Purpose: To report a technique for reconstruction of large, persistent, chronic, myopic macular holes using a combined human amniotic membrane graft and autologous retinal transplant (AMN-ART). Methods: Three patients with large, myopic macular holes that failed prior surgical attempts and underwent subretinal amniotic membrane graft with overlying autologous retinal transplant and short-term perfluorocarbon tamponade. Pre- and postoperative visual acuity (VA) and images were analyzed at 3, 6, and 9 months. Results: All 3 myopic macular holes remained closed at 9 months with resolution of central scotoma. The first case, a 69-year-old female, presented with a persistent macular hole whose minimum linear diameter was 1085 μm. Her pre-op VA of 20/200 improved by 9 months to 20/100. Secondly, a 72-year-old male with history of recurrent retinal detachment repair with silicone oil and persistent macular hole of 1134 μm presented with pre-op VA of 20/200, which was unchanged at 9 months. Lastly, a 76-year-old female with a persistent macular hole of 935 μm with preop VA of 20/80 improved by 9 months post-op to 20/50. No complications were encountered related to the grafts. Conclusion: Combined AMN-ART may provide a surgical option for repair of refractory, large, chronic myopic macular holes with underlying atrophy.

First Page

10.1097/ICB.0000000000001588

DOI

10.1097/ICB.0000000000001588

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