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  COVID-19 is Associated with Early Emergence of Preeclampsia: Results from a Large Regional Collaborative

  Theodore Jones, Sonia Sajja, and Ray Bahado-Singh

  Publication Date: 2-4-2022

  An increased risk of preeclampsia (RR=1.8), driven almost entirely by an increase in preterm preeclampsia (RR=2.85) was observed in COVID pregnancies (Table 1), with a dose-response relationship with symptomatology and severity (Table 2).

  ▪ The associations between COVID-19 disease and preeclampsia or preterm preeclampsia were independent of other risk factors, as demonstrated by the minimal changes in RR after adjustment for confounders (Table 1). However, African American (AA) COVID patients experienced preterm preeclampsia 1.9 times more than COVID patients of other races (10.1 vs 5.3), an increase not observed in control patients.

  ▪ The strength of the association for COVID with preeclampsia was comparable to the association of preeclampsia with chronic hypertension and nulliparity (data not shown).

  ▪ Increasing symptoms & severity of COVID-19 were associated with an increased risk for preeclampsia with placental lesions, even after adjustment for relevant covariates (Tables 1& 2).

  ▪ Non-Preeclamptic COVID patients had an increased trend of placental lesions compared to non-COVID patients, reaching significance for intravillous thrombin.

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  Racial disparities in risk for COVID-19 in pregnancy: Results from a large regional collaborative

  Theodore Jones, Sonia Sajja, and Ray Bahado-Singh

  Publication Date: 2-4-2022

  • Though previous studies have looked at both COVID-19 outcomes in pregnancy and racial disparities among patients with COVID-19, few have specifically studied racial disparities among pregnant patients with COVID-19.
  • Our goal in this study is to analyze the relationship, if any, between race and disparate COVID-19 risk in pregnancy.