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  Identifying Discrepancies in Diagnosis of PCOS with Use of Different Diagnostic Criteria

  Naveena Daram and Sangeeeta Kaur

  Publication Date: 5-2-2022

  INTRODUCTION
  Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Two main diagnostic criteria are used for PCOS: the Rotterdam and Androgen Excess Society (AES) criteria. Depending on which criteria is used, the diagnosis of PCOS may change. Therefore, our study investigates the discrepancies in the diagnosis of PCOS when using the Rotterdam versus the AES scale in the Beaumont Health System. This is clinically significant because a PCOS diagnosis should not be made lightly as it can come with many lifelong social, emotional, and medical implications.

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  COVID-19 is Associated with Early Emergence of Preeclampsia: Results from a Large Regional Collaborative

  Theodore Jones, Sonia Sajja, and Ray Bahado-Singh

  Publication Date: 2-4-2022

  An increased risk of preeclampsia (RR=1.8), driven almost entirely by an increase in preterm preeclampsia (RR=2.85) was observed in COVID pregnancies (Table 1), with a dose-response relationship with symptomatology and severity (Table 2).

  ▪ The associations between COVID-19 disease and preeclampsia or preterm preeclampsia were independent of other risk factors, as demonstrated by the minimal changes in RR after adjustment for confounders (Table 1). However, African American (AA) COVID patients experienced preterm preeclampsia 1.9 times more than COVID patients of other races (10.1 vs 5.3), an increase not observed in control patients.

  ▪ The strength of the association for COVID with preeclampsia was comparable to the association of preeclampsia with chronic hypertension and nulliparity (data not shown).

  ▪ Increasing symptoms & severity of COVID-19 were associated with an increased risk for preeclampsia with placental lesions, even after adjustment for relevant covariates (Tables 1& 2).

  ▪ Non-Preeclamptic COVID patients had an increased trend of placental lesions compared to non-COVID patients, reaching significance for intravillous thrombin.

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  Racial disparities in risk for COVID-19 in pregnancy: Results from a large regional collaborative

  Theodore Jones, Sonia Sajja, and Ray Bahado-Singh

  Publication Date: 2-4-2022

  • Though previous studies have looked at both COVID-19 outcomes in pregnancy and racial disparities among patients with COVID-19, few have specifically studied racial disparities among pregnant patients with COVID-19.
  • Our goal in this study is to analyze the relationship, if any, between race and disparate COVID-19 risk in pregnancy.

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  Descriptive Causes for Decreased Breast and Cervical Screenings in Sikh Populations

  Varneet Kaur Brar

  Publication Date: 5-2-2022

  INTRODUCTION
  Prior evaluations of breast and cervical cancer screens have found that immigrant South Asian women have lower compliance rates when compared to non-immigrant, white, or African American women (Shoemaker, 2016). It is widely accepted that early detection of cancers can improve outcomes for patients, and that screenings like mammography and pap smear tests are critical in this process. The aim of this study was to evaluate compliance rates for breast cervical cancer screens in Sikh women in Michigan, as well as to investigate attitudes which may be contributing to any disparities which may exist.

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  VBAC Success in Women with Diabetes Mellitus Types I + II: A Pilot Study

  Emma Randall, Rachel Taylor, Sarah Becker, and Zeynep Alpay-Savasan

  Publication Date: 5-2-2022

  Due to a rise in cesarean sections since the 1970s, the American College of Gynecology has acted to reduce unnecessary cesarean deliveries. In 2017, ACOG released clinical management guidelines for vaginal birth after cesarean delivery (VBAC), including a nomogram to predict VBAC success. This nomogram, developed by Grobman et al. (2007), explored factors impacting VBAC success for delivery at term for a singleton pregnancy. While the presence of diabetes was evaluated in the study, it was not found to be a significant factor in predicting outcome. This study will take a more detailed look at if pre-existing diabetes impacts a woman’s VBAC success.

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  Pelvic Organ Prolapse Quantification System- Teaching Residents with a 3D Model

  Jaber Saad, Patricia Franz, and Kurt Wharton

  Publication Date: 4-28-2022

  Objectives

  - Create and test the effectiveness of a simple model to teach POP-Q to current Ob/Gyn residents at Beaumont Health - Roya Oak

  - We hope to gain medical education knowledge to best guide future efforts to teach this material

  -- Secondarily, we surveyed recent graduates to examine their utilization of POP-Q and hope to inspire future research that will examine if using 3D model to teach POP-Q will make residents more likely to incorporate it in their practice as attendings.

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  Population-based Evaluation of Neonatal Abstinence Syndrome in Southeast Michigan

  Alia Ahmed Shah, Linnea Nierenberg, and Zeynep Alpay Savasan

  Publication Date: 4-28-2022

  Objectives

  - To identify the distribution of NaS in patients with opioid abuse in Beaumont Health System

  - To identify characteristics of these pregnant patients in our health system.

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  cfDNA in maternal blood and artificial intelligence: accurate prenatal detection of fetal congenital heart defects

  Sangeetha Vishweswaraiah, Perry Friedman, Ciara Talbot, Buket Aydas, Siddesh Southekal, Nitish K. Mishra, Chittibabu Guda, Ali Yilmaz, Uppala Radhakrishna, and Ray Bahado-Singh

  Publication Date: 10-21-2022

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  Effectiveness of Prenatal Screening Tests on Predicting Cardiac Anomalies

  Stephanie Y. Wong and Zeynep Alpay Savasan

  Publication Date: 5-2-2022

  INTRODUCTION
  Congenital heart disease (CHD) is the leading cause of birth defect-associated infant death. With 1 in 111 newborns born with CHD and an elevated infant mortality rate of 30-50%, early detection is imperative. Current prenatal screening mainly focuses on detecting chromosomal anomalies. However, the accuracy of these exams on detecting fetal cardiac abnormalities is not well researched. The primary goal of this study is to compare three prenatal screening tests’ potential, i.e anatomy ultrasound, nuchal translucency (NT), and cell-free DNA (cfDNA), in identifying risk for fetal cardiac anomalies.

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  Longitudinal metabolomics in the brain of mouse models with mild and severe traumatic brain injury

  Ali Yilmaz, Sigal Liraz Zaltsman, Esther Shohami, Juozas Gordevicius, Jack E. Sherman, Ray Bahado-Singh, and Stewart F. Graham

  Publication Date: 9-16-2022