Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson's Disease.
Document Type
Article
Publication Date
1-4-2021
Publication Title
Metabolites
Abstract
The gut microbiome can impact brain health and is altered in Parkinson's disease (PD). The vermiform appendix is a lymphoid tissue in the cecum implicated in the storage and regulation of the gut microbiota. We sought to determine whether the appendix microbiome is altered in PD and to analyze the biological consequences of the microbial alterations. We investigated the changes in the functional microbiota in the appendix of PD patients relative to controls (
Volume
11
Issue
1
First Page
29
Recommended Citation
Li P, Killinger BA, Ensink E, Beddows I, Yilmaz A, Lubben N, Lamp J, Schilthuis M, Vega IE, Woltjer R, Pospisilik JA, Brundin P, Brundin L, Graham SF, Labrie V. Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson's Disease. Metabolites. 2021 Jan 4;11(1):29. doi: 10.3390/metabo11010029. PMID: 33406628; PMCID: PMC7823437.
DOI
10.3390/metabo11010029
ISSN
2218-1989
PubMed ID
33406628