Bile salt hydrolase acyltransferase activity expands bile acid diversity.

Authors

Douglas V Guzior
Maxwell Okros
Madison Shivel
Bruin Armwald
Christopher Bridges
Yousi Fu
Christian Martin
Anthony L Schilmiller
Wendy M. Miller, Corewell Health
Kathryn M. Ziegler, Corewell Health
Matthew D. Sims, Corewell Health
Michael E. Maddens, Corewell Health
Stewart F. Graham, Corewell Health
Robert P Hausinger
Robert A Quinn

Document Type

Article

Publication Date

2-2024

Publication Title

Nature

Abstract

Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome because of their antimicrobial properties

Volume

626

Issue

8000

First Page

852

Last Page

858

Recommended Citation

Guzior DV, Okros M, Shivel M, Armwald B, Bridges C, Fu Y, et al. [Miller WM, Ziegler KM, Sims MD, Maddens ME, Graham SF] Bile salt hydrolase acyltransferase activity expands bile acid diversity. Nature. 2024 Feb;626(8000):852-858. doi: 10.1038/s41586-024-07017-8. Epub 2024 Feb 7. PMID: 38326608.

DOI

10.1038/s41586-024-07017-8

ISSN

1476-4687

PubMed ID

38326608