Brain Connectivity in Dystonia: Evidence from Magnetoencephalography.

Document Type

Article

Publication Date

6-2023

Publication Title

Advances in Neurobiology

Abstract

Magnetoencephalography (MEG) detects synchronized activity within a neuronal network by measuring the magnetic field changes generated by intracellular current flow. Using MEG data, we can quantify brain region networks with similar frequency, phase, or amplitude of activity and thereby identify patterns of functional connectivity seen with specific disorders or disease states. In this review, we examine and summarize MEG-based literature on functional networks in dystonias. Specifically, we inspect literature evaluating the pathogenesis of focal hand dystonia, cervical dystonia, embouchure dystonia, the effects of sensory tricks, treatment with botulinum toxin and deep brain stimulation, and rehabilitation approaches. This review additionally highlights how MEG has potential for application to clinical care of patients with dystonia.

Volume

31

First Page

141

Last Page

155

DOI

10.1007/978-3-031-26220-3_8

ISSN

2190-5215

PubMed ID

37338700

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