"Impact of Pre-PCI Troponin Levels on Outcomes Post-PCI in an Urban Ter" by Shaunak Mangeshkar, Mohammad Hamza et al.
 

Impact of Pre-PCI Troponin Levels on Outcomes Post-PCI in an Urban Tertiary Care Center

Document Type

Conference Proceeding

Publication Date

5-2025

Publication Title

Journal of the Society for Cardiovascular Angiography and Interventions

Abstract

Background: High pre-intervention troponin levels have been associated with worse post-procedural outcomes in patients with acute coronary syndrome (ACS). This study aims to determine the association between the highest pre-percutaneous coronary intervention (PCI) troponin levels and short as well as long term outcomes. Methods: The study included 2222 patients undergoing PCI for ACS. Baseline characteristics included demographic data, comorbidities were obtained. Outcomes were evaluated at 6 months and 1 year. Results: The baseline characteristics revealed no sex differences in our study cohort (female 70.62% vs male 67.07%, p=0.09). Analysis suggested a higher incidence of all-cause mortality at 30 days (aOR: 5.83, 95% CI 1.48-10.18, p=0.009) in patients with higher troponin levels but this difference was not significant at 6 months (p value=0.054). A significant difference was seen in cardiovascular mortality at 6 months (aOR 7.5, 95% CI 1.79-13.24, p¼0.01), all-cause mortality at 1 year (aOR 3.58, 95% CI 0.49-6.66, p=0.023) and cardiovascular mortality at 1 year (aOR 9.41, 95% CI 2.13-16.68, p =0.012). There was also a higher risk of cardiac arrest with higher troponin levels (aOR 8.35, 95% CI 3.16-13.54, p=0.002). Higher troponin levels did not correlate with the risk of recurrence of ACS(p=0.511). Conclusions: Higher pre-PCI troponin levels are associated with worsened short and long-term mortality as well as incidence of cardiac arrest. There was no clear association between troponin levels and ACS recurrence. Larger studies are needed to investigate this association further.

Volume

4

Issue

5 Suppl

First Page

42

Comments

Society for Cardiovascular Angiography and Interventions SCAI 48th Annual Scientific Sessions, May 1-3, 2025, Washington, DC

Last Page

43

DOI

10.1016/j.jscai.2025.103213

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