"Impact of Steroids on Managing Iatrogenic Pericardial Diseases After E" by Yong Hao Yeo, Aravinthan Vignarajah et al.
 

Impact of Steroids on Managing Iatrogenic Pericardial Diseases After Electrophysiological Procedures

Document Type

Conference Proceeding

Publication Date

4-2025

Publication Title

Heart Rhythm

Abstract

Background: Pericardial diseases are a recognized complication following electrophysiological (EP) procedures. While colchicine is a standard therapy, the potential benefits of adding steroids for iatrogenic pericardial diseases in the management remain unclear. Objective: We aimed to assess the impact of steroids on managing iatrogenic pericardial diseases after electrophysiological procedures. Methods: We utilized the TriNetX network to identify adult patients who had EP procedures and developed pericardial diseases (acute pericarditis/ pericardial effusion/ cardiac tamponade) within 1-month postprocedurally. Patients were categorized based on the use of steroids: steroids+ vs. steroids-. Those with a history of lupus or neoplasm were excluded. Patients were then followed for 1 year. Primary outcomes included all-cause mortality, all-cause hospitalization, and recurrence of significant pericardial diseases requiring interventions (pericardiocentesis, pericardiotomy). Results: After propensity score matching, 588 patients were included, with 294 patients in each cohort. Steroids+ group was associated with lower odds of recurrence of significant pericardial diseases requiring interventions (aOR 0.59, 95% CI 0.38–0.93, P50.02) than the steroids- group. There was no difference in the all-cause mortality (aOR 1.49, 95% CI 0.72–3.08, P50.28) and all-cause hospitalization (aOR 1.07, 95% CI 0.74–1.54). Conclusion: Steroids+ therapy in managing iatrogenic pericardial disease after EP procedures was associated with lower odds of recurrence of significant pericardial diseases.

Volume

22

Issue

4 Suppl

First Page

S333

Comments

Heart Rhythm Society Annual Meeting, April 24-27, 2025, San Diego, CA

Last Page

S333

DOI

10.1016/j.hrthm.2025.03.699

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