"Heterogeneity in Valvular Heart Disease-Related Cardiovascular Mortali" by Yong Hao Yeo, Ghee Kheng Lim et al.
 

Heterogeneity in Valvular Heart Disease-Related Cardiovascular Mortality Among Asian American Subgroups

Document Type

Conference Proceeding

Publication Date

4-1-2025

Publication Title

Journal of the American College of Cardiology

Abstract

Background: Significant heterogeneity in cardiovascular disease (CV) outcomes has been observed in Asian American ethnic groups. Reporting of Asian ethnicity in the US has evolved, with the option to identify the 6 largest Asian subgroups in the 2003 Standard Death Certificate. The CDC WONDER Mortality database is a national mortality and population database that contains national disaggregated Asian data starting in 2018. We studied differences in US valvular heart disease (VHD) mortality in Asian American subgroups. Methods: CDC WONDER data was used to study VHD-related CV mortality (2018-2023, ≥45 years old) in different Asian American subgroups. We calculated age-adjusted mortality rates (AAMR) per 100,000 individuals and proportional mortality ratios (PMR). Results: There were 4,946 VHD-related CV mortality in non-Hispanic Asians. Significant differences in AAMR were observed, highest in Filipinos (18.3), Japanese (17.3), Asian Indians (15.1), Vietnamese (10.1), Chinese (8.9), and lowest in Koreans (7.8). Filipinos tended to have the highest AAMR across all valve disease subtypes except mitral stenosis (Asian Indians). Chinese and Koreans had the lowest AAMR across all valve subtypes. There were significant differences in AAMRs over time among Asian subgroups. Asian subgroups had similar sex-related PMR, except for Asian Indians. Conclusion: Significant heterogeneity in VHD mortality exists in disaggregated Asian American subgroups in the US and warrants further investigation

Volume

85

Issue

12 Suppl

First Page

2243

Comments

American College of Cardiology Meeting, March 29-31, 2025, Chicago, IL

Last Page

2243

DOI

10.1016/S0735-1097(25)02727-5

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