Impact of Timing of Catheter Ablation for Ventricular Tachycardia on In-Hospital Outcomes
Document Type
Conference Proceeding
Publication Date
5-2024
Publication Title
Heart Rhythm
Abstract
Background: The optimal timing for ventricular tachycardia (VT) ablation in reducing VT recurrence and improving patient survival is an important but unresolved topic. Objective: This study aimed to evaluate the in-hospital outcomes among those who had early VT ablation versus those who had late VT ablation. Methods: Using the Nationwide Readmissions Database, 2,163 patients who underwent VT ablation between 2017 and 2020 were included. We categorized the cohort into early VT ablation (≤30 days) and late VT ablation (.30 days). The timing of VT ablation was determined based on the number of days between the index VT admission and VT ablation. The in-hospital outcomes were analyzed. Results: Our study included 1,585 (73.3%) patients who underwent early VT ablation and 578 (26.7%) patients who underwent late VT ablation. Post-procedurally, late VT ablation was associated with higher rates of early mortality (6.2% vs. 4.1%, p50.04), non-home discharge (15.2% vs. 11.4%, p50.02), and 30-day readmissions (23.9% vs. 12.1%, p,0.01). The length of hospital stay was longer in the late VT ablation group (5.4 vs. 3.8 days, p,0.01). Apart from vascular complications (9.9% vs. 6.4%, p,0.01), there was no significant difference in other procedural complications between the two groups. In multivariable analysis, late catheter ablation for VT was associated with higher odds of early mortality (aOR:2.94; 95% CI:1.05-8.20, p50.04), 30-day readmission (aOR:1.78; 95% CI:1.37-2.32, p,0.01) and vascular complications (aOR:1.48; CI:1.01-2.17, p50.05). Conclusion: Late VT ablation is associated with higher rates of early mortality, worse in-hospital outcomes, and greater 30-day readmission rates. These emphasize the potential mortality benefits of early catheter ablation for VT and suggest that early referral for VT ablation should be considered. Further research is needed to determine the optimal timing for VT ablation and its impact on long-term outcomes.
Volume
21
Issue
5S
First Page
S143
Recommended Citation
Tan MC, Ang QX, Yeo YH, Tolat AV, Russo AM, Sorajja D, et al. Impact of timing of catheter ablation for ventricular tachycardia on in-hospital outcomes. Heart Rhythm. 2024 May;21(5S):S143. doi:10.1016/j.hrthm.2024.03.543
DOI
10.1016/j.hrthm.2024.03.543
Comments
Heart Rhythm Society Annual Meeting, May 16-19, 2024, Boston, MA