Cardiac Arrhythmias During Pregnancy and Risk of Stillbirth
Document Type
Conference Proceeding
Publication Date
5-2024
Publication Title
Heart Rhythm
Abstract
Background: The incidence of arrhythmias among pregnant women has increased over the past decade. While the spotlight intensifies on managing these rhythms, national-level data assessing the risk of stillbirth in this population is limited. Objective: This study aimed to assess the risk of stillbirth among pregnant women admitted with arrhythmias. Methods: We used the Nationwide Readmissions Database and included all pregnant women with cardiac tachyarrhythmias (atrial arrhythmias, ventricular arrhythmias (VA), and supraventricular tachycardia (SVT)) (2017-2020). We compared the risk of stillbirth between pregnant women with cardiac arrhythmias and those without. Results: 7,517,975 pregnant women were identified: 11,091 (0.15%) having cardiac tachyarrhythmias. Among them, 7,503 (67.6%) had SVT, 2,340 (21.1%) had atrial arrhythmias, 906 (8.2%) had VA, and 342 (3.1%) had .1 arrhythmias. Overall, those with tachyarrhythmias had higher rates of stillbirth than those without (540 vs 368 per 100,000 deliveries; risk difference, 172 more per 100,000 deliveries). The stillbirth rate was the highest among those with VA, followed by atrial arrhythmias and SVT (1,545 vs. 598 vs. 400 per 100,000 deliveries). Among patients with arrhythmias, stillbirth rates were higher in those who underwent cardioversion/ defibrillation than those who did not (1,493 vs 529 per 100,000 deliveries; risk difference, 964 more per 100,000 deliveries). After adjustment for comorbid conditions, patients with VA were associated with significantly higher odds of stillbirth (aOR: 1.79; 95% CI: 1.02- 3.14, p50.04) compared to those without arrhythmias. However, a history of SVT and atrial arrhythmias was not associated with higher odds of stillbirth than those without arrhythmias (aOR: 0.82; 95% CI: 0.57- 1.19, p50.29, and aOR: 1.03; 95% CI: 0.60- 1.76, p50.93). Conclusion: VA was associated with significantly higher odds of stillbirth, whereas SVT and atrial arrhythmias were not. Additionally, cardioversion/ defibrillation was associated with higher stillbirth rates.
Volume
21
Issue
5S
First Page
S199
Last Page
S200
Recommended Citation
Yeo YH, San BJ, Tan MC, Ang QX, Tamirisa KP, Mehta N. Cardiac arrhythmias during pregnancy and risk of stillbirth. Heart Rhythm. 2024 May;21(5S):S199-S200. doi: 10.1016/j.hrthm.2024.03.661
DOI
10.1016/j.hrthm.2024.03.661
Comments
Heart Rhythm Society Annual Meeting, May 16-19, 2024, Boston, MA