Predictive Factors for High-Degree Atrioventricular Block and Conduction Abnormalities Following Transcatheter Aortic Valve Replacement: Insights From a Comprehensive Meta-Analysis

Document Type

Conference Proceeding

Publication Date

5-2024

Publication Title

Journal of the Society for Cardiovascular Angiography & Interventions

Abstract

Background: TAVR is a valuable therapeutic standard for symptomatic severe aortic stenosis in non-surgical candidates. However, it is associated with complications such as high-degree atrioventricular blocks (HAVB) and conduction abnormalities (CA). While various predictors have been discussed in the literature, a comprehensive meta-analysis is lacking. This study seeks to identify and evaluate the most prevalent predictors of HAVB and CA post-TAVR Methods: A systematic literature search identified studies on the predictors of HAVB and CA post-TAVR. Binary random-effects models estimated pooled odds ratios (OR) and 95% confidence intervals (CI). A leave-one out sensitivity analysis was performed. Heterogeneity was assessed using I2 statistics. Results: We analyzed a total of 14 studies involving 3757 patients. The mean age of the population studied was 79.9 years. Cardiovascular risk factors, along with atrial fibrillation, were increasingly reported in the HAVB and CA cohorts among the studies. Results indicated increased odds of post-TAVR HAVB and CA among patients with increased implantation depth (OR: 6.18 [1.16-32.88] p

Volume

3

Issue

5 Suppl

First Page

3

Comments

Society for Cardiovascular Angiography & Interventions SCAI 2024 Scientific Sessions, May 2-4, 2024, Long Beach, CA

DOI

10.1016/j.jscai.2024.101761

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