A Comprehensive Review of the Diagnosis and Management of Acute Liver Failure.

Document Type

Article

Publication Date

11-30-2023

Publication Title

Journal of clinical medicine

Abstract

Acute liver failure (ALF) is a rare and specific form of severe hepatic dysfunction characterized by coagulopathy and hepatic encephalopathy in a patient with no known liver disease. ALF carries a high morbidity and mortality. Careful attention should be given to hemodynamics and metabolic parameters along with the active surveillance of infections. Timely transfer and supportive management are important in an intensive care unit in a liver transplant center. Identifying patients who will and will not improve with medical management and may need emergent liver transplantation is critical. In this review, we provide a comprehensive update on the etiology, diagnosis, and management of ALF.

Volume

12

Issue

23

First Page

7451

DOI

10.3390/jcm12237451

ISSN

2077-0383

PubMed ID

38068503

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