The Contemporary Use of Intracoronary Brachytherapy for In-Stent Restenosis: A Review.

Document Type

Article

Publication Date

6-2023

Publication Title

Cardiovascular Revascularization Medicine : Including Molecular Interventions

Abstract

In-stent restenosis (ISR) has been a major limitation in interventional cardiology and constitutes nearly 10 % of all percutaneous coronary interventions in the United States. Drug-eluting stent (DES) restenosis proves particularly difficult to manage and poses a high risk of recurrence and repeat intervention. Intra-coronary brachytherapy (IBT) has been traditionally viewed as a potential treatment modality for ISR. However, its use was hindered by procedural complexity, cost, and the advent of newer-generation DES. Recent data suggests promising results regarding IBT for the treatment of resistant DES-ISR. This review addresses the mechanism of action of IBT, procedural details, and associated risks and complications of its use. It will also highlight the available clinical evidence supporting the use of IBT and the future directions of its utilization in the treatment of ISR.

Volume

51

First Page

67

Last Page

74

DOI

10.1016/j.carrev.2023.01.019

ISSN

1878-0938

PubMed ID

36732133

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