A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis.

Document Type

Article

Publication Date

5-30-2023

Publication Title

Cureus

Abstract

Histoplasmosis, also known as "Darling's disease," is caused by the dimorphic fungus Histoplasma capsulatum, which is distributed all over the world but is more common in Northern America. In this paper, we present the case of an adult patient with decompensated liver cirrhosis who had positive antigen test results for H. capsulatum and Blastomyces dermatitidis. Disseminated histoplasmosis was confirmed by means of additional antibody testing in a patient with septic shock complicated by multiorgan failure and duodenal perforation. A high index of suspicion is required for the detection of disseminated histoplasmosis.

Volume

15

Issue

5

First Page

e39744

DOI

10.7759/cureus.39744

ISSN

2168-8184

PubMed ID

37398709

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