Title

Radiation-Induced Vascular Disease-A State-of-the-Art Review.

Document Type

Article

Publication Date

3-30-2021

Publication Title

Frontiers in Cardiovascular Medicine

Abstract

Since the 1990s, there has been a steady increase in the number of cancer survivors to an estimated 17 million in 2019 in the US alone. Radiation therapy today is applied to a variety of malignancies and over 50% of cancer patients. The effects of ionizing radiation on cardiac structure and function, so-called radiation-induced heart disease (RIHD), have been extensively studied. We review the available published data on the mechanisms and manifestations of RIHD, with a focus on vascular disease, as well as proposed strategies for its prevention, screening, diagnosis, and management.

Volume

8

First Page

652761

Last Page

652761

DOI

10.3389/fcvm.2021.652761

ISSN

2297-055X

PubMed ID

33860001

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