Radiation-Induced Vascular Disease-A State-of-the-Art Review.

Authors

Eric H Yang
Konstantinos Marmagkiolis
Dinu V Balanescu, Beaumont Health Resident
Abdul Hakeem
Teodora Donisan, Beaumont Health Resident
William Finch
Renu Virmani
Joerg Herrman
Mehmet Cilingiroglu
Cindy L Grines
Konstantinos Toutouzas
Cezar Iliescu

Document Type

Article

Publication Date

3-30-2021

Publication Title

Frontiers in Cardiovascular Medicine

Abstract

Since the 1990s, there has been a steady increase in the number of cancer survivors to an estimated 17 million in 2019 in the US alone. Radiation therapy today is applied to a variety of malignancies and over 50% of cancer patients. The effects of ionizing radiation on cardiac structure and function, so-called radiation-induced heart disease (RIHD), have been extensively studied. We review the available published data on the mechanisms and manifestations of RIHD, with a focus on vascular disease, as well as proposed strategies for its prevention, screening, diagnosis, and management.

Volume

8

First Page

652761

Last Page

652761

Recommended Citation

Yang EH, Marmagkiolis K, Balanescu DV, Hakeem A, Donisan T, Finch W, Virmani R, Herrman J, Cilingiroglu M, Grines CL, Toutouzas K, Iliescu C. Radiation-Induced Vascular Disease-A State-of-the-Art Review. Front Cardiovasc Med. 2021 Mar 30;8:652761. doi: 10.3389/fcvm.2021.652761. PMID: 33860001; PMCID: PMC8042773.

DOI

10.3389/fcvm.2021.652761

ISSN

2297-055X

PubMed ID

33860001