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  Quality Improvement Study on Human Papilloma Virus (HPV) Vaccination uptake in HIV patients

  Hassan Akram, Paul Johnson, and Trini A Mathew

  Publication Date: 5-2-2022

  INTRODUCTION HPV is strongly associated with cervical cancer and cancers of vagina, vulva, penis, anus, rectum. In 2019, WHO identified vaccine hesitancy as top 10 global threats and planned to increase the HPV vaccine coverage. In June 2019 Advisory Committee on Immunization Practices (ACIP) in the US recommended shared clinical decision-making regarding HPV vaccinations in adults aged 26 through 45 years. The goal of this project is to evaluate the uptake of HPV vaccination and challenges in the HIV patients at Beaumont Hospital.

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  Resistance in Gram-Negative Bacteria in the Pediatric Patient Population by Age and Sex

  Benjamin Malamet and Matthew Sims

  Publication Date: 5-2-2022

  INTRODUCTION
  Previous research within the Beaumont Infectious Diseases Research Program found an increase in antibiotic resistance in adult males versus females. Furthermore, there is a peak in resistance in 18-29-year-old males, not seen in females. The origin of this early peak of antibiotic resistance in adults is unclear. This study examines these trends in the pediatric patient population.

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  Relatedness Of Urinary Escherichia Coli Strains And Connection Between Strain Type And Clinical Presentation

  Anet Szatkowski, Venkathesh Bai, and Matthew D. Sims

  Publication Date: 5-2-2022

  INTRODUCTION
  Urine is often not a sterile body fluid. When bacteria in the urine cause symptoms it is by definition a urinary tract infection (UTI). The specific symptoms will point toward a bladder infection (cystitis) or a kidney infection (pyelonephritis). Presence of bacteria in the urine without symptoms defines asymptomatic bacteriuria (AB). Despite requiring symptoms to diagnose a UTI, often AB is misdiagnosed as a UTI and treated with antibiotics when none are needed. Escherichia coli is the most common cause of UTIs accounting for 80-90% of community-acquired UTIs and 30-50% of nosocomial UTIs. The goals of this study are to determine whether specific strains of E. coli are associated with cystitis, pyelonephritis, or asymptomatic bacteriuria; whether specific strains are related to more serious infections; and whether specific strains can be geomapped to specific areas within Southeast Michigan using postal codes.