Thrombotic Thrombocytopenic Purpura Following Administration of the Moderna Booster Vaccine

Document Type

Article

Publication Date

3-24-2022

Publication Title

BMJ Case Reports

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a type of thrombotic microangiopathy that is characterized by microangiopathic haemolytic anaemia, consumption thrombocytopenia and organ injury. It is caused by a severe deficiency of ADAMTS13, which can be either congenital or acquired. There is a plethora of things that can cause the acquired form, including medications and infections. Vaccines have also been shown to cause TTP. In the midst of the COVID-19 pandemic, with multiple new vaccines being developed and distributed to the masses, the medical community needs to be aware of adverse events associated with these new vaccines. We present a case of TTP following administration of the Moderna booster vaccine.

Volume

15

Issue

3

First Page

e247576

DOI

doi: 10.1136/bcr-2021-247576

ISSN

1757-790X

PubMed ID

35332007

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