Renal Mass Biopsy is Associated With Fewer Radical Nephrectomies for Benign or Indolent Disease, Particularly for T1b Renal Masses.
Document Type
Article
Publication Date
1-2025
Publication Title
Urology practice
Abstract
INTRODUCTION: How renal mass biopsy (RMB) impacts patient management with T1 renal masses (T1RM) is unclear. We explore the association between RMB and utilization of active surveillance (AS), nephron-sparing interventions (NSI), and radical nephrectomy (RN).
METHODS: Data were analyzed retrospectively using the MUSIC-KIDNEY registry. Treatment received was analyzed using a fitted mixed-effects multinomial logistic-regression model.
RESULTS: Of 4062 patients, 19.6% underwent RMB. Factors associated with RMB included younger age, higher Charlson comorbidity score, tumor size > 2.0 cm and higher complexity tumors. AS was selected by 88%, 68%, and 27% of patients with benign, indeterminate, and malignant RMB findings. Non-malignant pathology at surgery was significantly (
CONCLUSIONS: Treatments received by T1RM patients undergoing RMB are different than when RMB is omitted, based on RMB results and several confounders. T1RM patients benefit from reduction in intervention for non-malignant disease, particularly when RN is planned. For every 7 biopsies of T1bRM performed, one RN was avoided.
Volume
148
Issue
156
First Page
101097
Recommended Citation
Boynton DN, Mirza M, Van Til M, Butaney M, Noyes SL, Seifman B et al Renal mass biopsy is associated with fewer radical nephrectomies for benign or indolent disease, particularly for T1b renal masses. Urol Pract. 2025 Jan;12(1):148-156. doi: 10.1097/UPJ.0000000000000710. PMID: 39302182.
DOI
10.1097/UPJ.0000000000000710
ISSN
2352-0787
PubMed ID
39302182
