Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2.

Document Type

Article

Publication Date

10-26-2021

Publication Title

Western Journal of Emergency Medicine

Abstract

INTRODUCTION: Coinfection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and another virus may influence the clinical trajectory of emergency department (ED) patients. However, little empirical data exists on the clinical outcomes of coinfection with SARS-CoV-2 METHODS: In this retrospective cohort analysis, we included adults presenting to the ED with confirmed, symptomatic coronavirus 2019 who also underwent testing for additional viral pathogens within 24 hours. To investigate the association between coinfection status with each of the outcomes, we performed logistic regression.

RESULTS: Of 6,913 ED patients, 5.7% had coinfection. Coinfected individuals were less likely to experience index visit or 30-day hospitalization (odds ratio [OR] 0.57; 95% confidence interval [CI], 0.36-0.90 and OR 0.39; 95% CI, 0.25-0.62, respectively).

CONCLUSION: Coinfection is relatively uncommon in symptomatic ED patients with SARS-CoV-2 and the clinical short- and long-term outcomes are more favorable in coinfected individuals.

Volume

22

Issue

6

First Page

1262

Last Page

1269

DOI

10.5811/westjem.2021.8.53590

ISSN

1936-9018

PubMed ID

34787549

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