"A Case of Pleomorphic Liposarcoma of the Superficial Distal Upper Extr" by Suraj Patel and Francisca Kartono
 

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Description

Pleomorphic liposarcoma (PLS) is the rarest subtype of liposarcoma, accounting for 5-10% of all liposarcomas.

PLS typically arises in deep soft tissue (e.g. retroperitoneal region, extremities) with aggressive behavior characterized by high rate of local recurrence (42%) and distant metastases (45%).

In contrast, ~25% of PLS develops within the dermis and superficial subcutaneous tissue. Superficial cases exhibit lower rates of recurrence and metastasis.

PLS is diagnosed under microscopic examination revealing multi-vacuolated pleomorphic lipoblasts. Without any specific immunohistochemical or molecular features, diagnostic challenges can arise when biopsy reveals scant lipoblasts.

Publication Date

5-9-2024

Disciplines

Dermatology

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2024 Alvin Yarrows Research Day at Corewell Health Hospital Farmington Hills, Farmington Hills, MI, May 9, 2024.

A Case of Pleomorphic Liposarcoma of the Superficial Distal Upper Extremity

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