Lichen Planus After COVID-19 Infection and Vaccination
Document Type
Article
Publication Date
3-2023
Publication Title
Archives of Dermatological Research
Abstract
Lichen planus (LP) is an inflammatory disorder believed to result from CD8 + cytotoxic T-cell (CTL)-mediated autoimmune reactions against basal keratinocytes. We present a review of LP following COVID-19 infection and vaccination. Literature searches were conducted on PubMed and Google Scholar from 2019 to 7/2022. 36 articles were selected based on subject relevance, and references within articles were also screened. 39 cases of post-vaccination LP and 6 cases of post-infection LP were found among case reports and case series. 152 cases of post-vaccination LP and 12 cases of post-infection LP were found in retrospective and prospective studies. LP is a rare complication of COVID-19 infection and vaccination that may be mediated by overstimulation of T-cell responses and proinflammatory cytokine production. However, it does not represent a limitation against COVID-19 vaccination, and the benefits of vaccination considerably outweigh the risks.
Volume
315
Issue
2
First Page
139
Last Page
146
Recommended Citation
Zou H, Daveluy S. Lichen planus after COVID-19 infection and vaccination. Arch Dermatol Res. 2023 Mar;315(2):139-146. doi: 10.1007/s00403-022-02497-y. PMID: 36471086.
DOI
10.1007/s00403-022-02497-y
ISSN
1432-069X
PubMed ID
36471086
