Hepatitis with Acute Liver Injury Secondary to Undifferentiated Viral Upper Respiratory Infection in an Immunocompetent Adult Patient

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Authors

Ryan Blackmer, Michigan State University College of Human Medicine Medical Student
Jeff Jones, Corewell Health West

Description

Acute upper respiratory infections (URIs) are self-resolving airway infections with symptoms such as cough, runny nose, congestion, low-grade fever, headache, malaise, sneezing, and facial pressure. Caused by over 200 viruses, URIs affect millions annually and last 1-3 weeks, with common complications such as ear, sinus, throat infections, and pneumonia. Rarely, URIs can lead to liver complications. The liver produces bile, clotting factors, breaks down toxins, and fights infection. Elevations in liver enzymes (ALP, ALT, AST) indicate liver injury. Severe URIs can rarely cause mild transient liver enzyme elevation mostly seen in immunocompromised patients or children. This report describes a novel case of an immunocompetent adult with viral hepatitis and acute liver injury following an undifferentiated viral URI.

Publication Date

5-9-2025

Disciplines

Emergency Medicine

Recommended Citation

Blackmer R, Jones J. Hepatitis with acute liver injury secondary to undifferentiated viral upper respiratory infection in an immunocompetent adult patient. Presented at: Research Day Corewell Health West; 2025 May 9; Grand Rapids, MI.

Comments

2025 Research Day Corewell Health West, Grand Rapids, MI, May 9, 2025. Abstract 1665