"Impact of Smoking on Coronary Volume-to-Myocardial Mass Ratio: An ADVA" by Kenneth R. Holmes, Gaurav S. Gulsin et al.
 

Impact of Smoking on Coronary Volume-to-Myocardial Mass Ratio: An ADVANCE Registry Substudy.

Document Type

Article

Publication Date

4-2024

Publication Title

Radiology. Cardiothoracic Imaging

Abstract

Purpose To examine the relationship between smoking status and coronary volume-to-myocardial mass ratio (V/M) among individuals with coronary artery disease (CAD) undergoing CT fractional flow reserve (CT-FFR) analysis. Materials and Methods In this secondary analysis, participants from the ADVANCE registry evaluated for suspected CAD from July 15, 2015, to October 20, 2017, who were found to have coronary stenosis of 30% or greater at coronary CT angiography (CCTA) were included if they had known smoking status and underwent CT-FFR and V/M analysis. CCTA images were segmented to calculate coronary volume and myocardial mass. V/M was compared between smoking groups, and predictors of low V/M were determined. Results The sample for analysis included 503 current smokers, 1060 former smokers, and 1311 never-smokers (2874 participants; 1906 male participants). After adjustment for demographic and clinical factors, former smokers had greater coronary volume than never-smokers (former smokers, 3021.7 mm

Volume

6

Issue

2

First Page

e220197

DOI

10.1148/ryct.220197

ISSN

2638-6135

PubMed ID

38483246

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